Clay Siegall proves himself as giant in targeted therapy development

In the last decades of the 20th century, the progress being made in the field of cancer research began to stagnate. While many forms of cancer had experienced dramatic reductions in overall mortality throughout the middle years of the twentieth century, towards the end of the 1980s, that lightning-quick pace of development had began to slacken noticeably. The industry needed some shaking up. As it happened, a few researchers were up to the task.


One of those researchers was a man by the name of Clay Siegall. Armed with a an MS from the University of Maryland in biology and a PhD in genetics from George Washington University, Clay Siegall was hired out of graduate school by the world-renowned cancer research organization, the National Cancer Institute. During his stint at the National Cancer Institute, Dr. Siegall began working on an entirely new class of drugs, called targeted cancer therapies. These were a category of drugs that contained a wide array of agents, using disparate principles in order to target the site of the malignancy directly.


One category of targeted cancer therapy drugs can be described as cytostatic. These are drugs that, simply put, seek to limit any further growth of the tumor or malignancy. They do this through a wide variety of means, but all of them have in common the complete interference with the mechanisms by which the cancer cells multiply. At the time, the majority of targeted cancer therapies were of the cytostatic variety. These were considered the easiest to engineer and had the most robust body of knowledge to which current researchers could refer.


However, there was a second type of targeted cancer therapies, much less well understood and hardly researched at all, up to that point. These drugs can be termed cytotoxic. The goal behind cytotoxic drugs is to completely kill all malignant cells in the organism. Dr. Siegall decided to focus on this area, which had been largely neglected.


Eventually, this work would lead Dr. Siegall to invent a new class of cytotoxic targeted therapy drugs, known as antibody drug conjugates. Today, antibody drug conjugates are employed as first-line treatment and save thousands of lives.


Andrew Rolfe Enhances The Ubuntu Fund’s Capital-Raising Activities

Andrew Rolfe who is one of the leaders of the Ubuntu Fund has played a pivotal role in helping the needy people in the society. With the growing number of disadvantaged persons in the community, the Fund decided to organize a funds drive that would raise adequate capital to enable them to benefit many people. This way, the management of the Ubuntu Fund organized for a gala dinner at the heart of London. At the invitation-only event, Andrew was mandated with the duty of ensuring that all the 300 guests were comfortable. Rolfe provided them with meals. He also brought in a Xhosa choir that entertained the guests with their tunes.

While planning for the event, the management of the same was certain that they would raise over £ 600,000. At the end of the event, the planners posited that they had managed to exceed their expectations as they raised over £ 603,000. They posited that they would use the money to expand the Fund’s school, which is based in Port Elizabeth, South Africa. In addition, the management would develop a pediatric clinic in the school campus. This way, they would have adequate resources that would allow for the accommodation of more needy students.

Some of the people who graced the occasion were Jacob Lief, the CEO of the Fund, and Sinesipho Rabidyani. When the guests finished eating, Sinesipho was invited to the podium. She shared her story of how her father’s drinking habit made her hate going home from school. Today, Rabidyani is a law student. Jacob posited that there was need for people to help the young ones.

About Andrew Rolfe

Andrew is the chairperson of the Fund. Previously, he worked for the Gap, PepsiCo and Pret A. Manger. He was heavily involved in enhancing the brand’s operations in the global market. He is also a director of TowerBook Capital Partners. The alumnus of the University of Oxford and Harvard Business School has extensive leadership experience.

Andrew Rolfe worked for True religion Apparel, Beverages & More, and J. Jill. Over the years, he has been seeking to enhance and expand the opportunities made available to the less fortunate children and their families.


Marc Sparks to Give

Marc Sparks is known for his avid contributions and for giving no less than the very best of himself to today’s modern culture with its many expediencies and needs: He is known as a giver all around and not really a taker; in fact, he has given to countless varied organizations to show his support and love, making mention that he is only a servant of God who has been blessed with many riches in his lifetime. He notes that the greatest joy of all lies in giving those riches back into the community and thus enriching lives while even bringing a few into eternity. Marc is an avid Christian as well who firmly holds to the commandments and teachings of Jesus Christ, especially as they regard giving and receiving: Marc believes that those who receive more ought to then give more; what comes around goes around, after all. Learn more:


Marc did not come from money, nor is he all about it in how he deals with his business and his giving. He holds that money can be a gift from God, one to give God thanks for while using it properly toward the further benefit of mankind. Marc believes that we as earth dwellers must also take care of this beautiful planet that God has bestowed upon us, all while loving it and nurturing it into generations to come. Marc is a believer in Creation, holding that what God created in the beginning is to be both respected and treated with the utmost of care; when you have a leader that is as genuinely rooted in the faith and in love for others, in combination with his talents and experiences that are uniquely out of this world, you are bound to get a good final result – that result is Marc Sparks. Learn more:


Marc has already written many books and continues in plans to write several more this year alone. Marc has taught in conferences and seminars as well. Marc even holds his own blog, in which he shares his victories, his losses, his joys, his struggles, his friends and family and so much more. is the best place to go to find out more on this matter. Did you also know that Marc also works with Habitat for Humanity, which he holds as one of his top go-to organizations when seeking to do some good?


He has also worked with Carpenters for Christ on many occasions and simply loves what this organization is all about. He has shared much with Carpenters for Christ. Carpenters for Christ has also shared much with him; he holds that he is always learning along the way and that he’s the one most blessed. Learn more:


About End Citizens United’ Primary Objective

As the name goes, End Citizens United is an agency committed to clearing the vices in America’s electoral system. Their main focus is to impact finance management in particular. They collaborate with like-minded donors who primarily fund their initiatives. It is unfortunate that the Supreme Court gave rise to super PACs in their 2010 decision in Citizen United. That decision has since affected U.S politics because of allowing black in the political field. End Citizens United is devoted to reversing the decision by all means. As such, the agency is set to elect leaders supporting campaign finance reforms. They are working towards ending Citizens United as it is the root of all evil in the electoral system.



Ways Through Which the Political Action Raises Funds



It prospected that before 2018 congressional midterm elections the agency will have raised $35 million. Many people came out to support the endeavor. Most of them were giving for their first time, a sign that End Citizens United is continually gaining prevalence. Donald Trump’s win came as a bombshell to the Democrats, hence significantly adding to their momentum in fighting back against his picks. The Republicans have purposed not to relent in their move towards ensuring a corruption-free America. The good thing is that many people are learning about it and are subscribing to their activities. Wealthy arrogant people like the Koch brothers attacked some people, and all the victims have joined hands with End Citizens United in kicking out such people.



Details About End Citizens United Administration



Tiffany Muller serves as the executive director and president of the agency. When joining End Citizens United, Muller knew she was committed to pushing for significant reforms through her platform. In her first trimester, Tiffany significantly improved growth of the startup by growing it with over 3 million members. Tiffany has an impressive record in her administrative duties. Before joining End Citizens United, she served at Democratic Senatorial Campaign Committee as the deputy political director. Her academic profile is equally impressive, which improves her leadership qualities quite extensively.



Co-Workers with Tiffany



Matt Burgess is an amazing political figure who has been in the industry for over 15years. He acts as the vice president of End Citizens United where he has proved to be of unmatched value. He has severally won Senate and gubernatorial campaigns, implying he is well informed. Jody Murphy is the other force to reckon in End Citizens United. He takes prides in his experience of over ten years in state legislative causes. Serving as a political director in the agency fits his capabilities quite perfectly. Mentioned are just some of the leaders. There are also other pillars like Adam Bozzi, Rajan Narang, Jordan Wood, Erin Fyffe, Devan Barber among others.


Walmart Carries a Range of Beneful Dog Foods for Your Pet’s Health and Happiness

Ensuring a healthy, well rounded diet for yourself isn’t always easy. However, Beneful makes sure that providing nutritious meals for your dog is simple. Beneful dog foods are available at Walmart, which means you can provide superior nutrition without having to shop at specialty stores or shell out a lot of money. Beneful healthy dog food recipes are available in stores and online for your convenience, and there are several wet and dry dog foods, and dog treats available.

For purchases made online, Walmart provides free 2-day shipping for orders costing more than $35. Beneful Originals come with real beef, real chicken or real salmon in sizes of 3.5 lb, 6.3 lb, 13 lb, 15.5 lb, 31.1 lb, 40 lb, and 44 lb bags. Prices and availability at Walmart range based on bag size and product, but be sure to look for specials and clearance products to save extra money. Along with real meat, Beneful Originals includes whole grains and vegetable accents. Omega fatty acids give your pet a healthy, shiny coat. Antioxidant Vitamin E protects your dog’s immune system. Each bowl includes a mix of crunchy kibble and tender bites for a taste and texture your pet will love.

Next time you are shopping for a healthy and balanced dog food, be sure to check out Walmart in person or online to select from Beneful’s range of beneficial dog foods. Also be sure to keep an eye out for coupons online, in stores, or in your local newspaper.

Alfonso De Angoitia Noriega – Reforming The Grupo Televisa To Ensure Seamless Growth

The media companies in Mexico are growing at a tremendous speed due to the booming economy of the country. Different sectors in the country are witnessing massive growth, and it is this increase that has trickled down to the media industry as well. As the competition in various areas continues to get fierce, the companies are looking for ways to market and advertise their products and services, and this is where media companies come to their rescue. The media industry provides the perfect platform for the companies from various sectors to market their products and reach out to a further audience in a seamless manner. Many new media companies are surfacing in Mexico from time to time, and some of the biggest businesses in Mexico are Evoga Entertainment, Cinemex, Grupo Reforma, Grupo CIE, and more.

Alfonso de Angoitia Noriega is a reputed figure in the world of media in Mexico and presently serves as the Vice President and Executive Managing Director of Grupo Televisa. Thanks to the reforms he has put into practice in the company, it has been growing steadily in the past few years, and its revenue has been sky-rocketing at a strong pace. Alfonso de Angoitia Noriega is known to be the right-hand man of the CEO of Grupo Televisa, Emilio Azcarraga Jean. It is the efforts made by Alfonso de Angoitia Noriega that helped in collaborating with the leading media conglomerate Univision.

Alfonso de Angoitia Noriega is also a well-known attorney and has previously served as the attorney of the CEO of Grupo Televisa. He is also one of the founding partners of the law firm named Mijares, Angoitia, Cortes-Fuentes S.C. He holds the position of director on board of many other companies, which includes Sky, Bolsa Mexicana de Valores, Pepsi Bottling Group Mexico and Empresas Cablevision. Grupo Televisa is the largest media firm in the Spanish-speaking world and is constantly innovating the industry with new and creative products. Alfonso de Angoitia Noriega has the experience of working with the reputed law firm such as White & Case LLP before co-founding his own law firm.

Follow Alfonso de Angoitia Noriega on Twitter

There Is No Rest For A Visionary

Adam Milstein achieved success in real estate by learning the intricate ways of the business. It takes a long time to earn money in a slow-moving industry. Adam developed a love for the characteristics of a business that requires patience and savvy. He had his first taste of real estate from his father who was a developer in Israel. Adam worked for his father and served in the Israeli military.

He managed to earn a Bachelor’s degree in his homeland and decided to move to the United States. Adam arrived in California with his wife and family. He studied at the University of Southern California and obtained a Master’s degree in Business Administration. Adam looked to apply the degree to Corporate America.

However, he was not satisfied by the types of offers he was getting from the companies recruiting him. He made a bold move and ventured out on his own as a real estate broker. Over time Adam learned the tricks of the trade and eventually became an investor in real estate. He is now a managing partner at Hagar Pacific Properties.

Adam Milstein had a vision at a very early age. He began working on it and did not allow himself to be distracted. Because of this Adam feels like he has never had a bad job. He has always been in the process of pushing towards the goals he sought for himself and his family. Adam and his wife founded the Adam and Mila Milstein Family Foundation as a way to reach out to those in need of the knowledge they have to offer. Philanthropy is very important to Adam Milstein at this point in his career. It makes all of his success in business more satisfying. The Adam and Mila Milstein Family Foundation focuses on educating people in the Jewish community. The organization works hard to strengthen the bond between Jewish Americans and the country of Israel. The foundation is run in the same manner as Adam’s business operations. It is important to understand how every aspect of the organization affects the participants that are involved.

Who We Support